Managing Feline Glucose Curves
purchasers actual property anchorage alaskaThe blood glucose curve is an ideal tool to determine the effectiveness of the insulin and identify the appropriate dose and frequency of administration. In general, maintaining blood glucose levels in a cat with diabetes between 120–300 mg/dL for the majority of the day will minimize the symptoms of diabetes and complications.
Veterinarians commonly adjust the insulin dose based on a blood glucose curve. When creating a glucose curve, remember that stress can affect the reliability of results, and the glucose curve is only one tool among others that can help diagnose and monitor diabetes mellitus. Your veterinarian will take clinical signs (or lack thereof) into account when contemplating any change in insulin therapy. The ultimate goal in regulating a cat with diabetes is to control the clinical signs adequately so your pet can enjoy a good quality of life.
How to complete a glucose curve
purchasers actual property anchorage alaskaThe procedure is as follows: shortly after your cat has been given its first meal (preferably at home), the first blood sample is taken just before the morning insulin is given. Blood samples are then collected every 2 hours throughout the day, for 12 hours if possible. This data is then plotted on a graph to generate a curve. Veterinarians will use the blood glucose curve to determine if any adjustments need to be made to the insulin dosage and feeding regimens.
How to interpret a glucose curve
purchasers actual property anchorage alaskaThe aim of treatment is to alleviate clinical signs of diabetes. To achieve this goal, veterinarians aim to keep blood glucose concentrations below the renal threshold and avoid hypoglycemia. They do this by maintaining blood glucose concentrations roughly between 120 to 300 mg/dL in cats for the majority of the day.3
The duration of insulin action is measured from the time of Vetsulin® (porcine insulin zinc suspension) injection, followed by a fall in blood glucose concentration, to the time that blood glucose exceeds the renal threshold concentration of 200 to 280 mg/dL in cats. Because stress can falsely increase the blood glucose values in cats, sometimes other blood tests are utilized to help manage the diabetic cat.
Measuring blood glucose
purchasers actual property anchorage alaskaTwo different options:
Blood samples can be taken to measure blood glucose or blood insulin concentrations. Two methods of taking blood samples to produce glucose curves include:
- Collection by your veterinarian of a venous blood sample from a peripheral vein. Plasma glucose concentrations are measured in a laboratory or by an in-clinic analyzer.
- At home, or in clinic collection of a drop of capillary blood from the pinna, analyzed using a handheld glucometer.
- Glucometers should be calibrated specifically for dogs and cats because of the difference in the ratios of glucose in plasma and red blood cells from humans.
- Readings may vary as much as 15% from samples submitted to the laboratory.
- Handheld meters are reasonably accurate. If a reading seems unusual or does not match the clinical signs, a second reading should be taken or another method used to confirm the blood glucose measurement.
Treatment is successful when the clinical signs of diabetes mellitus improve without inducing hypoglycemia.
After your cat stabilizes successfully, your veterinarian may perform routine rechecks every 2 to 4 months. Careful monitoring and control will help to limit long-term complications.
Blood glucose concentrations
purchasers actual property anchorage alaskaThe aim of therapy is to produce a blood glucose curve that approaches the average range and avoids potentially fatal hypoglycemia. A stable cat with diabetes exhibits a blood glucose range of around 120 to 300 mg/dL for most of a 24-hour period.