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Normal Blood Sugar Values, Molarity and Fluctuations

durham county north carolinadurham county north carolinaBy Dr. Ananya Mandal, MDReviewed by April Cashin-Garbutt, MA (Editor)

Blood sugar fluctuations

Blood sugar levels are tightly regulated by a variety of stimulations and mechanisms. This is important for metabolic homeostasis. Levels may fluctuate after fasting for long periods of time or an hour or two after consumption of food. Despite this, the fluctuations are minor. Normal human blood glucose levels remains within a remarkably narrow range.

durham county north carolinaIn most humans this varies from about 82 mg/dl to 110 mg/dl (4.4 to 6.1 mmol/l). The blood sugar levels rises to nearly 140 mg/dl (7.8 mmol/l) or a bit more in normal humans after a full meal. In humans normal blood glucose levels are around 90 mg/dl, equivalent to 5mM (mmol/l).

Since the molecular weight of glucose, C6H12O6, is about 180 g/mol, when calculated the total amount of glucose normally in circulating human blood is around 3.3 to 7g (assuming an ordinary adult blood volume of 5 litres).

durham county north carolinaIn other words in a healthy adult male of 75 kg (165 lb) with a blood volume of 5 litres (1.3 gal), a blood glucose level of 100 mg/dl or 5.5 mmol/l means a total of about 5 g (0.2 oz or 0.002 gal, 1/500 of the total) of glucose in the blood.

durham county north carolinaThis also means approximately 45 g (1½ ounces) in the total body water. Total body water includes more than merely blood and will be usually about 60% of the total body weight in men. 5 grams of glucose is about equivalent to a small sugar packet or a teaspoon full of sugar.

durham county north carolinaTo be considered a non-diabetic the American Diabetes Association recommends a post-meal glucose level less than 180 mg/dl (10 mmol/l) and a pre-meal blood glucose level of 90-130 mg/dl (5 to 7.2 mmol/l).

Molarity and mass concentration

durham county north carolinaBlood glucose is measured in terms of molarity, measured in mmol/L or millimoles per litre. In the United States, and to a lesser extent elsewhere, mass concentration, measured in mg/dL.If a mg/dL figure is to be converted to mmol/L, it is to be divided by 18 or multiply by 0.055. Similarly to convert a mmol/L figure to mg/dL it is to be multiplied by 18 or divided by 0.055.

Further Reading

Last Updated: May 13, 2019

Written by

durham county north carolinaDr. Ananya Mandal

Dr. Ananya Mandal is a doctor by profession, lecturer by vocation and a medical writer by passion. She specialized in Clinical Pharmacology after her bachelor's (MBBS). For her, health communication is not just writing complicated reviews for professionals but making medical knowledge understandable and available to the general public as well.

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